Callous Disregard is the account of how a doctor confronted first a disease and then the medical system that sought and still seeks to deny that disease, leaving millions of children to suffer and a world at risk.

In 1995, Dr. Andrew Wakefield came to a fork in the road. As an academic gastroenterologist at the Royal Free School of Medicine and the University of London, he was confronted by a professional challenge and a moral choice. Previously healthy children were, according to their parents, regressing into autism and developing intestinal problems. Many parents blamed the MMR...