Biomedical research could enable treating
the disease by effectively and specifically targeting
essential enzymes of this parasite. However, the parasite
has developed resistance to existing drugs making it
absolutely necessary to discover new drugs. We have
established a simple computational tool which analyses the
topology of the metabolic network of Plasmodium falciparum
to identify essential enzymes as possible drug targets. We
investigated the essentiality of a reaction in the metabolic
...