α-tocopherol and transition metal in scavenging mixture were evaluated as a possible oxygen scavenger. The effects of moisture, amount of transition metal, and thermal processing on oxygen scavenging capability were also investigated. Our results showed that α-tocopherol and transition metal had 6.72 cc O2/g oxygen scavenging capacity and 0.11 cc O2 /g·day oxygen scavenging rate. Nanoencapsulation technology was adopted for the possible oxygen scavenging activation system. α-tocopherol-loaded poly ε-caprolactone (PCL) nanoparticles were prepared by O/W emulsion...