Lyssaviruses are the etiological agents of rabies, one of the oldest documented and feared maladies in medical history. The last century has been particularly fruitful in regard to progress in Iyssavirus phylogenetic affinities, diagnostics, pathogenesis, molecular virology and epidemiology, pro- phylaxis and control. Yet, despite these academic and practical advances in research, the age-old horror evoked by rabies is still very real, with only four documented human recoveries once symptoms are realized. After decades of intense scrutiny and four recent books describing rabies and its viral...

Rabies is one of the oldest known pathogens, is incurable, and has the highest fatality rate of all infectious diseases. The Americas is the only region with bat rabies virus, including vampire bat rabies. The region is rich in cultural references and notable for many discoveries in the field, including the current vaccine potency test, diagnostic assay, conception of oral vaccines for wildlife, the first human survivor and the first successful canine rabies program executed at a broad level. Rabies remains the most important viral zoonosis, with tens of thousands of human fatalities and tens...

Rabies is one of the oldest known pathogens, is incurable, and has the highest fatality rate of all infectious diseases. The Americas is the only region with bat rabies virus, including vampire bat rabies. The region is rich in cultural references and notable for many discoveries in the field, including the current vaccine potency test, diagnostic assay, conception of oral vaccines for wildlife, the first human survivor and the first successful canine rabies program executed at a broad level. Rabies remains the most important viral zoonosis, with tens of thousands of human fatalities and tens...