Many recent developments in neuro-oncology relevant to clinical practice have contributed to improved patient care. The most im portant impact of these developments on treatment may have been a change in the attitudes of the neuro-oncologists involved in making decisions regarding patients with gliomas. From an era of uncertainty which led to therapeutic nihilism, we have entered one of active interventions based on objective parameters for the treat ment of gliomas, which may be either slow-growing or rapid kil lers. The histopathological characteristics of gliomatous lesions are intriguing,...