Research in electrophysiologic monitoring in anesthesia and intensive care has focussed mostly on questions pertinent for patient care: First how to quantitate drug effects on brain electrical activity and the degree of anesthetic-induced suppression of the central nervous system. Second, how to monitor functional impairment following cerebral ischemia and hypoxia. And third, how to differ entiate between drug-induced effects on the central nervous system and deleteri ous events related to reductions in cerebral blood flow and/or oxygen delivery. Even though progress has been achieved over...