l Tumor transformation produces numerous antigenic alterations ), particularly 2 among the glycoconjugates, sugars linked to each other, to lipids and to proteins, 3). Many blood group antigens are identified as glycoconjugates; they include the 4 ABO(H), MNT, Lewis, Ii and P antigens ). These determinants are particularly valuable since they can be understood in terms of their serology, chemical structure and biochemical genetics4-7). Their specific functions are not well understood; how ever, their position as terminal or penultimate sugars may assign them a special role lO as protective or...
l Tumor transformation produces numerous antigenic alterations ), particularly 2 among the glycoconjugates, sugars linked to each other, to lipids and...