There are many excellent books on general statistical methods in agricul- tural and biological research. These books cover a broad range of methods without going into detail on specialized topics. A number of topics including regression analysis, design of experiments, biological assay and categorical analysis have received in-depth treatment in specialized texts. Little appears in standard textbooks on experiments in which observations form sequences. The live weights of animals during a long-term experiment provide a familiar example of data forming a sequence, but many others occur: for...