Complex biological data is characterized by a high dimensionality, multi-modality, missing values and noisiness, making its analysis a challenging task. Complex data consists of primary data - the core data - produced by a modern high-throughput technology, and secondary data, a collection of all kinds of respective supplementary data and background knowledge. Furthermore, biological data often has an intrinsic hierarchical structure, e.g. species in the Tree of Life. In this book, novel visual data mining approaches for the analysis of gene expression data in biomedicine and for sequence...