Shear stress responsive genes in the vessel walls of the developing chicken embryo have a large impact on the development of the vasculature. To investigate the effect of altered blood flow on vessel formation, blood velocity profiles have to be known close to the vessel walls. However, the determination of the exact vessel geometry is difficult, because the vessels are very small (10 to 250 micrometres) and almost transparent. This thesis investigates several possibilities to stain the endothelium (the cell layer at the inner boundary of a vessel) of chicken embryo vasculature, using animals...
Shear stress responsive genes in the vessel walls of the developing chicken embryo have a large impact on the development of the vasculature. ...