Proteins are pharmaceuticals with high specificity
and activity at relatively low concentrations, but
to fully exploit their potential, an increased
effort has been put into the research and
development of suitable drug delivery concepts. The
success of a protein depends on the development of a
formulation that maintains the native protein
structure and activity during preparation of the
delivery system. A joint characteristic of many
delivery systems are the presence of two phases and
an interface. During preparation, proteins are
exposed to mechanical stress, to different...