Since the beginning of the modern era of algebraic topology, simplicial methods have been used systematically and effectively for both computation and basic theory. With the development of Quillen's concept of a closed model category and, in particular, a simplicial model category, this collection of methods has become the primary way to describe non-abelian homological algebra and to address homotopy-theoretical issues in a variety of fields, including algebraic K-theory. This book supplies a modern exposition of these ideas, emphasizing model category theoretical techniques.