A first-of-its-kind handbook, this text covers all the analytical techniques and methods commonly employed with oligonucleotides. With contributions from experts in the field, this handbook presents comprehensive coverage for analytical chemists, biochemists, biotechnologists, molecular biologists, and geneticists on the latest analytical technologies currently available. Topics covered include purity determination by HPLC, molecular weight determination, determination of hygroscopicity, analysis of bioburden, and analyses of ionic species by ion chromatography. A chapter on PAT and coverage...