Our brain houses the network of 10 billion neurons,
and glutamate is the major neurotransmitter
mediating rapid and excitatory synaptic
transmission. Interestingly, glutamate receptor
channels travel between intracellular compartments
in response to various extracellular stimulations.
Changes in the levels or localization of glutamate
receptor profoundly affect synaptic activity and
signal transduction. Neurological disorders, such as
schizophrenia, depression and stroke, result from
aberrant glutamate signaling in certain brain
regions. Therefore, research on glutamate receptor...