Analysis of single cells allows a complete
understanding of the heterogeneity that is present in
cell behavior and function. Current single-cell
analysis methods provide high-throughput information
about labeled biomolecules within cells, but often
cannot follow the dynamic processes occurring in
signaling pathways. New microfluidic methods have
separately allowed assays of fast timescale responses
or creation of uniform environments to study cell
behavior in a more quantitative manner. This book
focuses on microfluidic hydrodynamic trapping
techniques that aid in both fast...

This book delves into the recent developments in the microscale and microfluidic technologies that allow manipulation at the single and cell aggregate level. Expert authors review the dominant mechanisms that manipulate and sort biological structures, making this a state-of-the-art overview of conventional cell sorting techniques, the principles of microfluidics, and of microfluidic devices. All chapters highlight the benefits and drawbacks of each technique they discuss, which include magnetic, electrical, optical, acoustic, gravity/sedimentation, inertial, deformability, and aqueous...