The geometry of a dendritic spine influences the
dynamics of calcium in the spine and is regulated
during synaptic plasticity. For instance, a moderate
rise in calcium can cause elongation, while a very
large increase in calcium causes fast shrinkage and
the eventual collapse of a spine. In this book, we
presented computational models for the calcium
mediated spine-stem restructuring. This expansion
and shrinkage depends on the frequency of the
synaptic input to a spine as well as the activation
of the calcium channels located on the spine head
membrane. We are using computational...