Based on the understanding of the molecular basis of skin diseases, this truly international book supports the reader to understand the mode of action of new and established therapies. Thus, by explaining the molecular pathology with its applications for therapy, it provides the reader with an up-to-date knowledge of the therapy of skin disease and helps to understand ongoing and new developments in the field. Written and edited by international and renowned dermatology experts from Europe, America and Asia, it also includes regional concepts of therapies.

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Recently, many ground-breaking steps have been made towards better understanding NO/cGMP/PKG pathways, its components, substrates, and their localization within a given cell. These advances were only possible due to the development of sophisticated new techniques in the field. In Guanylate Cyclase and Cyclic GMP: Methods and Protocols expert researchers in the field seek to provide an overview of novel techniques to identify various elements of the NO/cGMP/PKG pathway and further characterize their function, signaling, localization, and importance on a cellular level and in whole...