Interventional Neuroradiology is a minimally invasive approach in the treatment of vascular diseases of the central nervous system. This exciting new issue of Neuroimaging Clinics, Guest Edited by Dheeraj Gandhi, includes such topics as CT guided percutanous biopsies of the head and neck, dangerous collaterals in the head and neck, and treatment of carotid-cavernous fistulae. This issue is a must-have clinical resource.