Impurity profiling and drug degradation pathways are essentials features for regulatory acceptance of any new drug entity. Despite of technological advancements in pharmaceutical analysis, structural elucidation of drug molecules, impurities produced during formulation remains challenging tasks for researchers. Unique chemical behavior, complex properties and interactions of different functional groups involved in active pharmaceutical ingredients along with different chemical environments with excipients and storage condition further complicate the issues. Furthermore isolation and...
Impurity profiling and drug degradation pathways are essentials features for regulatory acceptance of any new drug entity. Despite of technological ad...
Cancer has a high morbidity and a very high mortality, being the most common cause of death worldwide. Breast cancer is the second most common cancer overall, that represents about 12% of all new cancer cases and 25% of all cancers in women. Bioinformatics is an essential tool in target discovery and the in silico analysis is an integral part of it, facilitating the selection of the most important targets for a disease under study. The input of biochemistry to pharmacology has grown. Molecular pharmacology puts more emphasis on the mode of action of drugs, albeit it becomes clear that the...
Cancer has a high morbidity and a very high mortality, being the most common cause of death worldwide. Breast cancer is the second most common cancer ...