The use of anticancer agents as part of the treatment strategy has greatly improved the overall prognosis of cancer. In clinical practice, chemotherapy for cancer often requires a combination of drugs and therefore understanding the clinical pharmacology of anticancer drugs is imperative for achieving optimal benefits from use of these agents. The aim of this thesis was to investigate the biochemical and cytotoxic effects of naturally occurring compounds, such as resveratrol, resveratrol analogs, piceatannol, gallic acid, Avemar, and heavy water alone and/or in combination with clinically...