The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key signal stimulating this appearance was identified as the presence of unfolded proteins within the cell. It is now known that this is a key mechanism enabling cells to survive a multitude of physical, chemical and biological stresses.
Since the promulgation of the 'molecular chaperone' concept as a general cellular function to control the process of correct protein folding, a large number...
The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearan...
This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D).
Brings together contributions from the leaders in the arena of clinical immunotherapy, not limited to the diabetes field exclusively, in order to delineate a road-map that would lead to future clinical trials.
The book integrates information from human and animal studies.
The book considers T1D within the broader context of autoimmune disease.
The format contains several discussions, which address...
This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes ...
