How should regional cities develop regional development strategies for their sustainable future? How can such strategies work effectively? Regional cities are now at a crossroads: will they decline or be regenerated under the impacts of globalization? Their sustainable regeneration as creative regional centers will play a decisive role in their sustainable development as a whole, but only with viable regional spatial strategies that strengthen the network of cities and their hinterlands. The concern here lies in urban regeneration and strategic spatial planning at the city-region level....