Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials.

Highlights of the Second Edition include:

• Pharmacokinetics
• Modeling and simulation
• Formulation and routes of administration
• Toxicity evaluations
• The assessment of drug absorption and metabolism
• Interspecies scaling
• Lead...