Enclosed ecosystem experiments have gained in popularity as research tools in ecological science, particularly in the study of coastal aquatic environments. These systems provide scientists with a degree of experimental control that is not achievable through field experiments. Yet to date, techniques for systematically extrapolating results from small-scale experimental ecosystems to larger, deeper, more open, more biologically diverse, and more heterogeneous ecosystems in nature have not been well developed. Likewise, researchers have lacked methods for comparing and extrapolating...