The Pacific Symposium on Biocomputing (PSB) 2008 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2008 will be held on January 4-8, 2008 at the Fairmont Orchid, Big Island of Hawaii. Tutorials will be offered prior to the start of the conference.PSB 2008 will bring together top researchers from the US, the Asian Pacific nations, and around the...