Jugular vein and carotid artery cannulations are among the most widely used surgeries in research labs around the world. These cannulations are extremely important for confirmed intravenous delivery of test substances and arterial blood collection. Cannulation reduces the stress of multiple sampling as observed in association with tail vein or orbital sinus techniques (Ling, 2003; Flynn, 1988; Cocchetto, 1983). Very few adverse effects, including a possible rise of corticosterones and a decrease in platelets, are associated with indwelling catheters except under chronic conditions (Fagin,...