Working with DNA is a guide to the materials and methods that are used in the recombinant DNA laboratory and is designed to help the novice understand how specific laboratory techniques work, but also has sections that may stimulate the thinking of experienced researchers. It isn't a book of step-by-step protocols and recipes, but is intended to broaden and strengthen the foundation of the reader so that working with DNA becomes more natural and make them aware of the many ways that a molecular research question may be addressed.