Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions.

This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein...

Incorporating the most important and cutting-edge developments in the field, this bestselling text introduces newcomers to the key theories and techniques of social network analysis and guides more experienced analysts in their own research.

New to this edition:

• A chapter on data collection, covering a crucial phase of the research process
• Fully updated examples reiterate the continued importance of social network analysis in an increasingly interconnected world
• Detailed 'Further Reading' sections help you explore the wider literature
...

Incorporating the most important and cutting-edge developments in the field, this bestselling text introduces newcomers to the key theories and techniques of social network analysis and guides more experienced analysts in their own research.

New to this edition:

• A chapter on data collection, covering a crucial phase of the research process
• Fully updated examples reiterate the continued importance of social network analysis in an increasingly interconnected world
• Detailed 'Further Reading' sections help you explore the wider literature
...

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The first comprehensive collection of its kind, this handbook addresses the problem of knowledge production in criminology, redressing the global imbalance with an original focus on the Global South.

A unique contribution to discussions of social theory, this book examines pre-20th century histories and discussions that culminated in the classical period of sociology, how they were lost, and why they remain important today.