Proceedings of the 2nd International Symposium on Combination Therapies for Cancer held in Sicily (Italy) in May 1992. Papers address the mechanism of action and rationale for use of biological response modifiers (BRM) in the treatment of cancer. BRM's possible role in treating infectious diseases,

Arachidonic acid metabolites are known to playa regulatory role in a number of biological systems, in which they function as microenviron- mental hormones and intracellular signal mediators. One of the most exciting areas of research of these compounds is the one that studies the relationship between prostaglandins and tumor cell growth and function. In the last few years there has been an extraordinary evolution of data on prostaglandins (and related compounds) and cancer. This vol- ume is based on papers presented at the 1986 International Confer- ence on Prostaglandins and Cancer organized...

All living organisms are exposed to rapidly changing environmental conditions which may lead to external stress. How organisms cope with stress - especially on the molecular level - is explained in Stress Proteins. Cells react to external stress - where the temperature-induced reaction known as "heat shock response" is the best studied example of stress - by activating special genes and subsequently synthesizing stress proteins. Surprisingly, this stress response is not only similar for all types of stress but even the involved stress proteins are virtually identical in all organisms...