This volume is a critical edition of the 1587 treatise by Oliva Sabuco, New Philosophy of Human Nature, written during the Spanish Inquisition. Puzzled by medicine's abject failure to find a cure for the plague, Sabuco developed a new theory of human nature as the foundation for her remarkably modern holistic philosophy of medicine. Fifty years before Descartes, Sabuco posited a dualism that accounted for mind/body interaction. She was first among the moderns to argue that the brain--not the heart--controls the body. Her account also anticipates the role of cerebrospinal fluid, the...