The Pacific Symposium on Biocomputing (PSB) 2006 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2006 will be held January 3?7, 2006 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference. PSB 2006 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange...