This text provides comprehensive coverage of the latest advances in the development, preparation and application of topical and transdermal therapeutic systems. It explores the biochemistry and treatment of various skin diseases as well as the structure and function of the skin, adverse dermal response to drug formulations, mechanisms of drug transport through barrier membranes, and methods for measuring and modulating percutaneous permeation.

Recent advances in our understanding of the development and morphology of normal skin has led to improved methods to deliver therapeutic compounds to selected targeted areas both within the skin and systemically. This reference provides a clear overview of current pharmaceutical and cosmeceutical practices in the management of both major and minor skin disorders and provides an expansive overview of novel drugs and therapies used to treat these conditions.

The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin absorption and the various governmental and industrial programs concerned with skin permeation and toxicity. These include alternative in silico, in vitro, and in vivo strategies to conduct studies for regulatory requirements. To make room for this...