Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models. Thus, this book allows a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing the conserved trends in development. This book culminates with state-of the art knowledge on hematopoietic development in human species and discussions of the most recent breakthroughs with relevance to both researchers and clinicians.

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Ce travail porte sur l'analyse de l'ontogenese du systeme hematopoietique chez l'embryon de souris. Dans l'embryon de vertebres, l'hematopoiese s'effectue en deux vagues successives. Les precurseurs de la premiere vague, generes dans le Sac Vitellin, presentent des capacites de maintenance et de differenciation reduites, ceux qui sont issus de la seconde presentent toutes les caracteristiques des cellules souches hematopoietiques. Le facteur de transcription GATA-3 est exprime dans l'embryon au cours de la determination et de la generation des cellules souches et il n'est jamais exprime aux...

Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models. Thus, this book allows a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing the conserved trends in development. This book culminates with state-of the art knowledge on hematopoietic development in human species and discussions of the most recent breakthroughs with relevance to both researchers and clinicians.

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