Leishmaniasis is a tropic and subtropical disease affecting humans and other mammals, discovered 100 years ago, and known to be spread by the sand flea. The conference lecture sessions are a topical compendium of the most pertinent aspects of recent research and provide a focus for future research in the area of control. The workshop summaries deal
Leishmaniasis is a tropic and subtropical disease affecting humans and other mammals, discovered 100 years ago, and known to be spread by the sand fle...
V Pentostam, an uncharacterized complex of Sb and carbohydrate derived from gluconic acid, is concentrated by Leishmania amastigotes via protein binding. Biochemical consequences of the interaction of amastigotes with Pentostam are inhibition of parasite bioenergetics and inhibition of ATP synthesis. REFERENCES 1. J.C. Mottram and G.H. Coombs. Enzyme activities of amastigotes and promastigotes and their inhibition by antimonials and arsenicqls. Exper. Parasitol. 59:151 (1985). 125 2. S.L. Croft, K.D. Neame and C.A. Homewood. Accumulation of Sb] sodium stibogluconate by Leishmania mexicana...
V Pentostam, an uncharacterized complex of Sb and carbohydrate derived from gluconic acid, is concentrated by Leishmania amastigotes via protein bindi...
