The covalent attachment to deoxyribonucleic acid in vivo of a large number of different types of chemical compounds (both normal cellular constituents such as proteins and amino acids, and also exogenous compounds such as drugs, carcinogens, etc. ) have been shown to exert profound effects upon cells. Four research activi- ties, formerly considered to be totally independent, relate to this problem of nucleic acid adducts--(1) normal covalent attachment of DNA to membranes, protein linkers in chromosomes, etc.; (2) the roles of radiation and chemical enhancement of DNA adduct formation in cell...

The science of photobiology is a dynamic multidisciplinary field whose relevance to the needs of man is growing more apparent each day. Publicity about supersonic transports (the SSTs) and spray cans, their possible dele terious effects on the stratospheric ozone layer, and the possible resultant consequences of enhanced solar ultraviolet radiation on man and his envi ronment have helped to focus attention on both the beneficial and the detri mental effects of light. In addition, considerable activity is currently being directed toward harnessing solar energy as one solution to the world...

The goals of the science of photobiology can be divided into four categories: to develop (I) ways to optimize the beneficial effects of light on man and his environment, (2) methods to protect organisms, including man, from the detrimental effects of light, (3) photochemical tools for use in studies of life processes, and (4) photochemical therapies in medicine. To achieve these goals will require the knowledgeable collaboration of biologists, chemists, engineers, mathematicians, physicians, and physicists; because photobiology is a truly multidisciplinary science. While a multi- disciplinary...

The goals of the science of photobiology can be divided into four cate- gories: to develop (1) ways to optimize the beneficial effects of light on man and his environment, (2) methods to protect organisms, including man, from the detrimental effects of light, (3) photochemical tools for use in studies of life processes, and (4) photochemical therapies in medicine. To achieve these goals will require the knowledgeable collaboration of biologists, chemists, engineers, mathematicians, physicians, and phys- icists, because photobiology is a truly multidisciplinary science. While a...

A stone carving from the 14th century B.C. records that the Egyptian pharaoh Akhenaten (born Amenhoteph IV) and his wife, Nefertiti, recognized the importance of sunlight to life. In fact, Akhenaten initiated a monotheistic religion, with Aton, the sun, as God. One of his daughters be- came the wife of King Tut Ankamon, the spelling of whose name indicates a return to the old religion and an eclipse of interest in photobiology among the pharaohs. A renewal of interest in photobiology in modern times was climaxed in 1928 by the establishment of an international organization for photobiology...