In 1978 the Dutch Genetic SOciety organized a symposium on the genetic aspects of the origin of tumor cells. The objective of this symposium was to reach an overview of the state of knowledge in a number of quite different fields related to each other through the genetics of the initiation of tumor cells. This monograph contains the brought-up-to-date contributions of this symposium. Herein discussed is the extent that characteristics of tumor cells can be considered as a phenotype. The possible role of somatic mutation and repair of genetic damage is studied and the analysis of genes with...

The Boerhaave Committee for postgraduate Medical Education decided to organize a course on cancer treatment covering selected solid tumors, in which they felt important chan ges were emerging in the basic biologic, diagnostic and therapeutic concepts. Current management of cancer patients is intimately dependent on precise morphologic diagnosis, clinical staging and the proper application of all treat ment modalities. Many prominent investigators and clinicians of major can cer centers in the United States, Canada, and Europe con tributed by lecturing and during the panel discussions. This...