This book explores aspects of the development and regeneration of the of the rote nervaus system, beginning with fundamental considerations of borneobox genes in vertebrate pattern formation. Two papers em phasize the roJe of mause Hox genes in patterning: the Hox-2 complex in the branchial arches and Hox-7 at later stages of development, par ticularly in the spinal cord and brain. The importance of borneobox genes and other transcription factors in patterning the Drosophila embryo is weil known. With the discovery of homologaus genes in higher verte brates including man, we now possess the...

This authoritative volume brings together chapters by international experts on key issues in developmental neurobiology. A central theme is the way in which current work on the trophic and cellular interactions that regulate the growth and guidance of regenerating nerves offers hope for the neurologically damaged patient.