With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include:
chemical synthesis of modified RNA
expansion of the genetic alphabet in nucleic acids by creating new base pairs
chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides
nucleic-acid-templated...
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetu...
Der Band versammelt 17 Beitrage des bereits verstorbenen Judaisten Gunter Mayer (1936-2004) und des Tubinger Neutestamentlers Michael Tilly, seines langjahrigen Mitarbeiters. Das breite Spektrum an Themen aus dem Bereich des hellenistischen und rabbinischen Judentums umfasst u.a. Arbeiten zur Geschichte der Bibel, zur Sozialisation und Erziehung des Kindes, zum antiken Funeralwesen und zur Rezeptionsgeschichte biblischer Prophetentexte.
Der Band versammelt 17 Beitrage des bereits verstorbenen Judaisten Gunter Mayer (1936-2004) und des Tubinger Neutestamentlers Michael Tilly, seines...
After the deciphering of the human genome and the genomes of many other organisms, the investigation of the function of gene products and their orchestral interplay is now one of the most important challenges in the life sciences. In "Nucleic Acid and Peptide Aptamers: Methods and Protocols," expert researchers contribute state-of-the-art methods focused on these two vital molecule types which are so often employed for in vitro selection procedures. Divided conveniently into two distinct parts beginning with nucleic acid aptamers and ending with peptide aptamers, the volume provides...
After the deciphering of the human genome and the genomes of many other organisms, the investigation of the function of gene products and their orc...
This volume provides protocol references covering recent developments in the aptamer field. Within the last decade, aptamers have become more and more popular, and their sophisticated biophysical properties together with their ability to be easily modified and, thus, adapted to various regimens makes them a very promising class of compounds. Divided into three sections, the book covers selection, a series of analytical methods to assess biophysical properties of aptamer-target interactions, as well as various applications of aptamers. Written for the highly successful Methods in...
This volume provides protocol references covering recent developments in the aptamer field. Within the last decade, aptamers have become more and m...
