For several decades the electron microscope has been the instrument of choice for the examination of biological structures at high resolution. Biologists have be come familiar with the techniques and pitfalls of sample preparation and with the interpretation of the images obtained. The purpose of this book is to introduce the biologist to a number of new imaging techniques that are now becoming avail able to supplement and even extend the information that can be obtained from the now-traditional electron microscope. Some of these techniques are still at the experimental stage, while others,...

A fundamental problem in cell biology is the cause of aging. The solution to this problem has not yet been obtained because, (l) until recently, it was not possible to image living cells directly. The use of low-energy (soft) X rays has made such imaging possible, perhaps thereby allowing the aging process to be understood and possibly overcome (a result that may well generate further social, moral, and ethical problems). Fortun- ately this is not the only aspect of cell biology amenable to soft X-ray imaging, and it is envisaged that many less controversial studies--such as investigations of...

For several decades the electron microscope has been the instrument of choice for the examination of biological structures at high resolution. Biologists have be come familiar with the techniques and pitfalls of sample preparation and with the interpretation of the images obtained. The purpose of this book is to introduce the biologist to a number of new imaging techniques that are now becoming avail able to supplement and even extend the information that can be obtained from the now-traditional electron microscope. Some of these techniques are still at the experimental stage, while others,...