Despite their effectiveness in the evaluation of new pharmacological compounds, controlled clinical trials are sometimes inadequate. Using data from the literature as well as from the author's own experience with clinical trials, Human Experimentation: Methodologic Issues Fundamental to Clinical Trials addresses such inadequacies and tries to provide solutions. This work is the first to thoroughly examine these unsolved inadequacies and problems with the design and the execution of clinical trials and, more importantly, to provide solutions for these problems. It is important for...
Despite their effectiveness in the evaluation of new pharmacological compounds, controlled clinical trials are sometimes inadequate. Using data from t...
"Knowledge desires increase - it is like fire that first must be kindled by some external agent, but which will always afterward propagate itself." Johnson, Letter to William Drummond August 13, 1776 The therapeutic effectiveness and safety of beta-adrenergic blocking drugs has been well established in patients with essential hypertension and arteriosclerotic cardiovascular disease. These drugs are useful in primary protection against cardiovascular morbidity or mortality in patients with essential hypertension and secondary protection (mor bidity and mortality in patients with myocardial...
"Knowledge desires increase - it is like fire that first must be kindled by some external agent, but which will always afterward propagate itself." Jo...