Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-, and various growth factors, is essential during embryogenesis. The establishment of concentration gradients of these morphogens is vital for developmental patterning, ensuring that distinct differentiated cell types appear in the right place and at the right time in forming tissues. Written and edited by experts in the field, this volume explores how morphogen gradients are generated and interpreted during development. The contributors examine the regulation of morphogen synthesis, trafficking, and diffusion, as well as the...

Frankenstein Vigilante: The Incorruptibles is the first volume in a steampunk/fantasy series set in The Smoke, a city-state ruled by the Commission and their mobster allies the Silencios. Cerval Franks - ne Frankenstein - and his crew set out to release The Smoke's citizens from their servitude, aided by a cast of memorable characters including young journalist Shelly Mary Ventura, warrior woman Paulina Ellamova and Chavalier leader Dalton Trager Rhineheart. Violent, sexy and provocative, The Incorruptibles brings a new and exciting perspective to steampunk fiction, while retaining all the...