Short chain fatty acids (SFCA) are synthesized by the colonic microflora primarily from non-absorbed carbohydrate; there is also some limited production from non-absorbed protein. In contrast, SFCA are not normally present in the diet. During the past 15 years SFCA have attracted considerable interest in human nutrition, physiology and pathophysiology as a result of the realization that SFCA represent an important mechanism for carbohydrate and calorie conservation and may play a role in various types of colitides and possibly in colonic neoplasia. In addition, SFCA, produced in large amounts...
Short chain fatty acids (SFCA) are synthesized by the colonic microflora primarily from non-absorbed carbohydrate; there is also some limited producti...
Recent advances in understanding the role of protein dysmetabolism in neurodegeneration was the theme of the Fondation IPSEN meeting addressing Genotype-Proteotype-Phenotype relationships. Experts from international laboratories contributed to the current volume to produce a comprehensive overview of the role of protein misfolding in neurodegeneration. Links between genotype and protein characteristics and between proteotype and clinical phenomenology were discussed across diseases categories. Progress in understanding the role of abnormalities of protein metabolism may lead to the...
Recent advances in understanding the role of protein dysmetabolism in neurodegeneration was the theme of the Fondation IPSEN meeting addressing Gen...
