Why We Wrote This Book This book is about using graphs to explore and model continuous multi variate data. Such data are often modelled using the multivariate normal distribution and, indeed, there is a literatme of weighty statistical tomes presenting the mathematical theory of this activity. Our book is very dif ferent. Although we use the methods described in these books, we focus on ways of exploring whether the data do indeed have a normal distribution. We emphasize outlier detection, transformations to normality and the de tection of clusters and unsuspected influential subsets. We then...

Why We Wrote This Book This book is about using graphs to explore and model continuous multi variate data. Such data are often modelled using the multivariate normal distribution and, indeed, there is a literatme of weighty statistical tomes presenting the mathematical theory of this activity. Our book is very dif ferent. Although we use the methods described in these books, we focus on ways of exploring whether the data do indeed have a normal distribution. We emphasize outlier detection, transformations to normality and the de tection of clusters and unsuspected influential subsets. We then...

The International Statistical Institute was founded in 1885 and is therefore one of the world's oldest international scientific societies. The field of statistics is still expanding rapidly and possesses a rich variety of applications in many areas of human activity such as science, government, business, industry, and everyday affairs. In consequence, the celebration of the Institute's centenary in 1985 is of considerable interest not only to statisticians but also more widely to the international scientific community. As part of its centennial celebration planning the Institute decided to...

This book collects the proceedings of the 10th Workshop on Model-Oriented Design and Analysis (mODa). A model-oriented view on the design of experiments, which is the unifying theme of all mODa meetings, assumes some knowledge of the form of the data-generating process and naturally leads to the so-called optimum experimental design. Its theory and practice have since become important in many scientific and technological fields, ranging from optimal designs for dynamic models in pharmacological research, to designs for industrial experimentation, to designs for simulation experiments in...

This volume contains pioneering contributions to both the theory and practice of optimal experimental design. Topics include the optimality of designs in linear and nonlinear models, as well as designs for correlated observations and for sequential experimentation. There is an emphasis on applications to medicine, in particular, to the design of clinical trials. Scientists from Europe, the US, Asia, Australia and Africa contributed to this volume of papers from the 11th Workshop on Model Oriented Design and Analysis.