The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed.
Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune,...
The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome...