The octanol-water partition coefficient is a laboratory-measured property of a substance. It provides a thermodynamic measure of the tendency of the substance to prefer a non-aqueous or oily milieu rather than water (i.e. its hydrophilic/lipophilic balance). Partition coefficients are used extensively in medicinal chemistry, drug design, ecotoxicology and environmental chemistry. The partition coefficient is recognized by governmental and international agencies (U.S. Environmental Protection Agency, OECD) as a physical property of organic pollutants equal in importance to vapour pressure,...
The octanol-water partition coefficient is a laboratory-measured property of a substance. It provides a thermodynamic measure of the tendency of the s...
* Presents theoretical models for interpreting and predicting solubilities in solutions. * Evaluates the collection techniques used to obtain solubility data and presents the most appropriate methods. * Reviewed and commissioned by IUPAC, an internationally renowned society.
* Presents theoretical models for interpreting and predicting solubilities in solutions. * Evaluates the collection techniques used to obtain so...
