This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population....

Environmental epidemiology is the study of the environmental causes of disease in populations and how these risks vary in relation to intensity and duration of exposure and other factors like genetic susceptibility. As such, it is the basic science upon which governmental safety standards and compensation policies for environmental and occupational exposure are based. Profusely illustrated with examples from the epidemiologic literature on ionizing radiation and air ollution, this text provides a systematic treatment of the statistical challenges that arise in environmental health studies and...

Environmental epidemiology is the study of the environmental causes of disease in populations and how these risks vary in relation to intensity and duration of exposure and other factors like genetic susceptibility. As such, it is the basic science upon which governmental safety standards and compensation policies for environmental and occupational exposure are based. Profusely illustrated with examples from the epidemiologic literature on ionizing radiation and air pollution, this text provides a systematic treatment of the statistical challenges that arise in environmental health studies...