Thedevelopmentoftechnologiesforhigh-throughputmeasurementofgene expression in biological system is providing powerful new tools for inv- tigating the transcriptome on a genomic scale, and across diverse biol- ical systems and experimental designs. This technological transformation is generating an increasing demand for data analysis in biological inv- tigations of gene expression. This book focuses on data analysis of gene expression microarrays. The goal is to provide guidance to practitioners in deciding which statistical approaches and packages may be indicated for their projects, in...

Thedevelopmentoftechnologiesforhigh-throughputmeasurementofgene expression in biological system is providing powerful new tools for inv- tigating the transcriptome on a genomic scale, and across diverse biol- ical systems and experimental designs. This technological transformation is generating an increasing demand for data analysis in biological inv- tigations of gene expression. This book focuses on data analysis of gene expression microarrays. The goal is to provide guidance to practitioners in deciding which statistical approaches and packages may be indicated for their projects, in...

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.