This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists. They may hold the opinion that genetics has run its course since Mendel read his paper on peas in 1865. "Why bother with classical genetics," they may ask....
This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new...
On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu- nologists from analyzing it as energetically as they have analyzed the adaptive immune system during the past two decades. But while its phylogenetic origins are indeed ancient, and though it is "of the first type," there is nothing crude, nothing unsophisti- cated, and nothing "inferior" about innate immunity. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last...
On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu- nologists from analyzing it as...
