To analyze internal movement, I developed an anatomical classification system based on combinations of possible joints and muscle contractions resulting in movement of the hand, which maintains its same absolute location in the signing space. Using this coding system, I mapped the frequency of internal movement types across a languages set of internal movement signs. These results allowed me to speculate on the properties of the articulator that most readily allow sign languages to change or innovate. In addition, I looked at the prevalence of marked and unmarked hand configurations and...

Several sulphur & nitrogen containing heterocyclic compounds have been studied because of their interesting biological properties such as Anti-bacterial, Anti-fungal, Anti-hypertensive, Anti-HIV, Anti-inflammatory, Anti-microbial, Anti-rheumatic, Aldose reductase inhibitor, ATP-sensitive potassium channel opener. 1,4-Benzothiazine forms an important class of heterocyclic system. Several studies are available for 1, 4-Benzothiazine formation and their application in drugs. 1, 4-benzothiazine and thiazoles constitute an important class of sulfur and nitrogen heterocytes. The utility of thiazole...

The primary role of medicinal chemist has become one of improving upon existing drugs by increasing their potency and duration of action and by decreasing toxic side effects as well as creating new drugs by molecular modifications. Very useful synthetic analogue with improved therapeutic properties can be obtained from a single lead compound by structural modification. The same applies to the group of natural lactone of plant origin, one of the diverse and important system of natural products with a broad spectrum biological activities. Physiological activity of natural lactone is known ever...

India has a rich heritage of knowledge on plant based drugs used in traditional system of medicine. A large number of plants and remedies were pharmacologically tested and useful data was generated for development of therapeutic agents. Scientists are searching newer avenues and material for drug development and for that they are search for new medicinal plants, which are till date not have been exploited to their fullest extent (except traditional systems). The rich biodiversity of the tropical region all over the world have attracted scientific attention and tropical region of lower plane...

The International Maritime Organisation (IMO), International Transport Workers' Federation (ITF) and the International Labour Organisation (ILO) have rendered yeomen service to protect the rights of Seafarers'. India is a founder member of the International Labour Organisation (ILO). In spite of this fact India has not ratified quite a few conventions. India has a very long coastline and is a major supplier of seafarers to the world. The Constitution of India contains no special provision for Seafarers' in particular to protect their rights. Shipping has an international and multifarious...

Gouty arthritis is one of the major problems whose prevalence has doubled in the past decades. Studies have estimated that over 20 million people suffer from gout every year. Allopurinol, the major drug used in the treatment has very poor bioavailability and results in many severe side effects. This book addresses this problem as it has large social implications on the society. One of the recent approaches to explore new pharmaceutical drug is the design of the cocrystals. It has an added advantage that as both the compounds are already approved by the FDA no more drug trial is necessary...