Proteolysis is essential for life. From the breakdown of proteins in food for biosynthesis, through to antigen processing in the immune system, the blood cl- ting cascade, and the hormone-regulated remodelling of female reproductive tissues in adult mammals - proteolysis governs functionality, homeostasis, and fate at the levels of the cell and the entire organism. For the cancer cell, intracellular prote- ysis carried out by caspases and the proteasome must be enlisted and controlled to allow it to escape apoptosis. Functioning on the cancer cell surface or in the extracellular milieu,...
Proteolysis is essential for life. From the breakdown of proteins in food for biosynthesis, through to antigen processing in the immune system, the bl...
A flood of data indicate the importance and the relevance in both respiratory and extrapulmonary disease of Chlamydia pneumoniae infection today. Antibody prevalence rates in Western countries reach 50% in the adult population and remain high in old age suggesting a high rate of reinfection. Chlamydia pneumoniae can cause upper respiratory tract infections, like pharyngitis and sinusitis as well as bronchitis and more than 10% of community-acquired pneumonia. Recent data suggest a possible association of Chlamydia pneumoniae infection with wheezing and adult-onset asthma. However, the most...
A flood of data indicate the importance and the relevance in both respiratory and extrapulmonary disease of Chlamydia pneumoniae infection today. Anti...
Chlamydia pneumoniae is now recognized as an important human pathogen. Chlamydia pneumoniae is involved in 5%-15% of community acquired pneumonias, and recent data indicate its relevance in severe pneumonia and as a respiratory pathogen in immunocompromised subjects.
Chlamydia pneumoniae is now recognized as an important human pathogen. Chlamydia pneumoniae is involved in 5%-15% of community acquired pneumonias, an...
This text explores the management of chronic obstructive pulmonary disease (Copd), including the role of bacterial infections and the efficacy of antimicrobial therapy in acute exacerbations of chronic bronchitis (AECD).
This text explores the management of chronic obstructive pulmonary disease (Copd), including the role of bacterial infections and the efficacy of anti...
This book covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; and many other relevant subjects, including new approaches to targeting proteolysis for therapy.
This book covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass ...
Comprehensive guide to diagnosis and management of respiratory infections. Complete chapters dedicated to patients with comorbid conditions. Recognised authors from Milan and Athens.
Comprehensive guide to diagnosis and management of respiratory infections. Complete chapters dedicated to patients with comorbid conditions. Recognise...
